Is a benign enlargement of the prostate. The prostate gland is a small organ with the size of a walnut that is just beneath the bladder and surrounds the urethra. It produces sperm feeding liquid. However, at the age of 50, it tends to be enlarged, due to hormonal imbalance, the effect of which is the squeeze of the urethra. This results in blockage and inflammation of the bladder, leading to symptoms such as slow urination both during the day and at night. If not treated, the effects are: bladder damage, urinary tract infections, bladder stones and even kidney failure.
Complications
XU may be a progressive disease. If not treated, there is a risk of significant bladder blockage leading to high residual urine, which in turn can lead to recurrent urinary tract infection and stone formation. When clogging becomes even worse, kidney swelling (hydronephrosis) can be due to high bladder pressures and, ultimately, sudden inability to urinate. In such a case, it is necessary, surgery using a resectoscope tool to remove a large portion of the prostate enlargements, if possible. This operation is called transurethral resection of the prostate (TURP).
Treatment
There are two main groups of drugs. First, alpha1-blockers (eg Hytrin, Xatral) help to relax the tone of the prostate and bladder neck. They are taken at bedtime, 70% effective, but have a 10% chance of causing dizziness at night, due to lowering of blood pressure. However, they do nothing to reduce the size of the prostate. The second group are 5-alpha-reductase inhibitors (eg, Proscar, Avodart) that reduce male hormone dihydrotestosterone (DHT) within the prostate and thus reduce prostate size. They are for large glands (> 30 ml size), but the combination with alpha1-blockers is necessary for the first few months.
